Skreeny seems to have been built during the 1690s. It is recorded as a seat of the Cullen family by both Taylor and Skinner and Wilson in the 1780s. During the Famine period it was used as a temporary fever hospital. The townland was in the possession of the Earl of Leitrim by the time of Griffith's Valuation where the only buildings recorded area a gate house and offices, valued at £1 10s. Skreeny House is labelled as "in ruins" on the 25-inch Ordnance Survey map of the 1890s. The Irish Tourist Association survey of the 1940s recorded that it was "the ruins of one of the principal gentry seats in the area".